Brand Name: SGONEK
Price: $2 -$3/Gram
Place of Origin: Shaanxi, China
Certification: ISO FDA SG COA MSDS
Grade: Food Grade Pharmaceutical Grade
Payment Terms: T/T, Western Union, MoneyGram
Product Name: | Rosuvastatin calcium | Cas No.: | 147098-20-2 |
Molecular Formula: | C22H27CaFN3O6S+ | Purity: | 99%min |
Brand Name: | SGONEK | Certification: | ISO FDA SG COA MSDS |
Product Name | Rosuvastatin Calcium |
CAS No. | 147098-20-2 |
Purity | 99% |
Appearance | White Powder |
Molecular Formula | C22H27CaFN3O6S+ |
EINECS No. | 1308068-626-2 |
Description: Rosuvastatin is a member of pharmaceutical class known as statins, used for lowering blood cholesterol and antihyperlipidemia. |
ITEMS |
SPECIFICATION |
Appearance |
A white to off-white powder |
Identification |
Meets the requirements |
Specific Rotation |
+15.0°~ +21.0° |
Chloride |
≤0.1% |
Sulphate |
≤0.1% |
Enantiomer |
≤0.5% |
Related Substances |
Diastereomers ≤0.5% 5-oxo-Rosuastatin ≤0.3% Photodegradation impurity 1≤0.3% Photodegradation impurity 2 ≤0.3% Rosuvastatin lactone ≤0.3% Rosuvastatin tert-butyl ≤0.3% Any unknown impurity: ≤0.2% Total impurities ≤1.0% |
Water |
≤3.0% |
Heavy Metals |
≤0.002% |
Residual Solvents |
Methanol ≤0.3% Ethyl ether ≤0.5% Acetone ≤0.5% Acetonitrile ≤0.041% Toluene ≤0.089% Isopropyl ether ≤0.5% Ethyl acetate ≤0.5% Tetrahydrofuran ≤0.072% Tert-butyl alcohol ≤0.5% Acetic acid ≤0.5% |
Assay (on dried basis) |
98.5 ~ 102.0% |
Rosuvastatin is a competitive inhibitor of the enzyme HMG-CoA reductase, having a mechanism of action similar to other statins.
Rosuvastatin 's approximate elimination half life is 19 hours and its time to peak plasma concentration are reached in 3–5 hours following oral administration.
Putative beneficial effects of rosuvastatin therapy on chronic heart failure may be negated by increases in collagen turnover markers as well as a reduction in plasma Coenzyme Q10 (CoQ10) levels in patients with chronic heart failure.